unable to receive email exchange 2010

I had to restart my server and now when I try to send email to a user from outside the network I am getting 5.7.1 errors

tested via telnet
telnet my.server.net 25

responds 220 internal.server.local
mail from:me@mine.com
responds ok
rcpt to:me@server.net
I get unable to relay

what I am I doing wrong
Who is Participating?
MAS (MVE)Technical Department HeadCommented:
Do you have anonymous ticked in the Default Receive connector properties?
if not please tick , restart Transport service and try.

Do a SMTP test from http://mxtoolbox.com/diagnostic.aspx
HalCHubAuthor Commented:
on hub Anonymous is ticked an so is TLS
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HalCHubAuthor Commented:
if I

rcpt: me@internal.server.local it works fine
HalCHubAuthor Commented:
echo  server.net returns

250 internal.server.local
HalCHubAuthor Commented:
Attempting to send a test email message to me@server.net using MX store.server.net.
  Delivery of the test email message failed.
 Additional Details
The server returned status code 550 - Mailbox unavailable. The server response was: 5.7.1 Unable to relay for me@server.net
Exception details:
Message: Mailbox unavailable. The server response was: 5.7.1 Unable to relay for me@server.net
Type: System.Net.Mail.SmtpFailedRecipientException
Stack trace:
 at System.Net.Mail.SmtpTransport.SendMail(MailAddress sender, MailAddressCollection recipients, String deliveryNotify, Boolean allowUnicode, SmtpFailedRecipientException& exception)
 at System.Net.Mail.SmtpClient.Send(MailMessage message)
 at Microsoft.Exchange.Tools.ExRca.Tests.SmtpMessageTest.PerformTestReally()
Zacharia KurianAdministrator- Data Center & NetworkCommented:
A few questions:

1. Is your exchange box virtualized?
2. Do you have any devices/network  such as spam filtering appliances/applications?
3. Do you have issues internally sending and receiving emails?

Did you try recreating the relay connector?
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