VB.Net - Application attempted to perform an operation not allowed by the security policy

Good Day Experts!

I have a bit of a quandry today.  We are updating email hosting and have to setup the local Outlook profile for each user machine.  Several have worked great and 3 machines are giving me trouble.  An informative message box appears telling me what the issue is but I am not sure what to do to implement it.  I have tried searching the net in order to help but am not finding a resolution.

"Application attempted to perform an operation not allowed by the security policy.  To grant this application the required permission, contact your system administrator, or use the Microsoft .Net Framework Configuration Tool."

I am not sure where the .Net Configuration Tool is and what I would have to change if I found it.  

Can you assist in my dilemma here?

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Bob LearnedCommented:
What framework version are you targeting?

Mscorcfg.msc (.NET Framework Configuration Tool)

Mscorcfg.msc has been removed from the .NET Framework version 4 and later versions. This documentation applies only to earlier versions of the .NET Framework.

Security Changes in the .NET Framework 4

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Jimbo99999Author Commented:
We have installed .Net Framework 2.0 that it appeared to be "wanting".  We ended up configuring Outlook locally for these few machines but have more to do next week.  The Web hosting app provides an automated way to update outlook initiated from the app.  We have a few more to do next week.  I will take a look at the data you have provided.

Thanks for the information,
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