Outlook to Exchange - password prompt keeps showing up

Hi, I'm having an issue where 3 out of 4 people using an exchange server (Exchange 2007) are getting a pop up asking for their password at random times through the day (using Outlook 2013). If you hit cancel 2 times, you can go back to using outlook like normal and all folders (public or otherwise) are accessible.  Also, typing in the password in doesn't make the boxes go away.

I've read up on this a little already and I went in and checked the authentication methods for all the exchange application folders under IIS manager (changed them with no affect so I changed them back). I also tried changing the authentication method from basic to NTLM and also tried negotiate under the More Settings button for the individual account settings, and the pop up still comes up under all of them. I read somewhere that disabling the Autodiscover can get rid of this but they want to use Autodiscover and I know using Autodiscover is possible without having the pop up, so I didn't even try this.  Does anyone have anything else I can do to get rid of this password pop up?
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Matt KendallTech / Business owner operatorAsked:
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Rajitha ChimmaniCommented:
Next time they receive a popup check if the account was locked out. Sometimes its possible that account was locked and got unlocked automatically after 15 mins.
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Matt KendallTech / Business owner operatorAuthor Commented:
I disabled the account lockout policy (and kerberos just to see if that was doing anything) and it still happens.
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