I changed the Domain Administrator password (7 sites, 8 DCs, 7 subnets) a couple of days ago, now none of my remote sites can connect to Exchange 2007 with Outlook 2007 or 2010 clients. The primary location of the Exchange server, email flow works perfectly. The sites are connected thru an MPLS cloud & I can remotely administer all DCs & User workstations. I can telnet to port 25 from the remote sites (intermittently), but I cannot telnet to port 587. We also use receive connectors for each server to allow relay. Please help.