Re running /PrepareAD and /PrepareDomain after RU13 update on Exchange 2013 ?

Ok, I am experiencing a permissions issue in exchange 2013 where I am getting an access denied error on certain daily operations. The advise I am getting is to put the install DVD in and run the setup again with the /PrepareAD switch followed by the /PrepareDomain switch to make sure that all the permissions are set correctly in the domain. Sounds like sound advise but here is my question:

During the RU13 install I was required to run those same Active Directory preparation commands so I assume that it had something different to add than the original. So do I run them from the original install media and then again from the RU update or will the RU13 update files do the same thing? I would think that the RU would be cumulative and do the trick but I cant find any information on this. Any advise would be appreciated!
Sean SizemoreAsked:
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Simon Butler (Sembee)ConsultantCommented:
RU13? No such thing for Exchange 2013. The latest is CU6 for Exchange 2013.

However you should use whatever Cumulative Update you are on. All cumulative updates are the complete product, so you just run setup.exe from the extracted files - with the switches as required.

Simon.
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Sean SizemoreAuthor Commented:
Sorry......is it Friday yet?  =)   That is the roll-up for 2007, been up to my ears in migrations and it was almost time to go home! Thank you for the response. The system in question is on CU5 so I think I will go ahead and apply CU6 and kill two birds. Thanks again.
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