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This solution worked, I was able to establish the port-channel <br />
access mode, default vlan on ESXI, &nbsp;Load balancing set to IPHASH on ESXI , and load balancing on CISCO was set to src-dst-ip
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CCNA-SKE, can you post your config for the switch? I am doing this now and I would like the reference<br />
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Thx
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I need to setup port-channeling from 4 NICS in the ESXi (ver 5.1) &nbsp;to 4 ports in Cisco 4500 using &nbsp;ether channel group mode <br />
ON, I will have to use these port-channel in access mode, I think this design is similar to VLAN tagging using external VLAN tagging (EST mode)<br />
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Do I have to use certain load balancing balancing &nbsp; on Cisco and ESXi ? or it will work with different load balancing on both ends, Also do i have to have same vlan number on ESXI and Cisco 4500 in order this to work ?
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I need to setup port-channeling from 4 NICS in the ESXi (ver 5.1)  to 4 ports in Cisco 4500 using  ether channel group mode 
ON, I will have to use these port-channel in access mode, I think this design is similar to VLAN tagging using external VLAN tagging (EST mode)

Do I have to use certain load balancing balancing   on Cisco and ESXi ? or it will work with different load balancing on both ends, Also do i have to have same vlan number on ESXI and Cisco 4500 in order this to work ?

Port-channeling between ESXI(5.1) and Cisco 4500( ver 15.2)

Networking software modules are interfaced with a framework implemented on the machine's operating system that implements the networking functionality of the operating system. The best known frameworks are the TCP/IP model and the OSI model. Systems typically do not use a single protocol to handle a transmission. Instead they use a set of cooperating protocols, sometimes called a protocol family or protocol suite.[9] Some of the best known protocol suites include: IPX/SPX, X.25, AX.25, AppleTalk and TCP/IP. Other protocols indirectly related to networking include the hypertext transfer protocol (HTTP) and its related technologies, Dynamic Host Configuration Protocol (DHCP), Domain Name Server (DNS) and other Internet protocols.

Networking Protocols

VMware, a software company founded in 1998,  was one of the first commercially successful companies to offer x86 virtualization. The storage company EMC purchased VMware in 1994. Dell Technologies acquired EMC in 2016. VMware’s parent company is now Dell Technologies.

VMware has many software products that run on desktops, Microsoft Windows, Linux, and macOS, which allows the virtualizing of the x86 architecture.  Its enterprise software hypervisor for servers, VMware vSphere Hypervisor (ESXi), is a bare-metal hypervisor that runs directly on the server hardware and does not require an additional underlying operating system.

VMware

Network security consists of the policies adopted to prevent and monitor authorized access, misuse, modification, or denial of a computer network and network-accessible resources. Network security involves the authorization of access to data in a network, and covers a variety of computer networks; conducting transactions and communications among businesses, government agencies and individuals. Networks can be private, such as within a company, and others which might be open to public access.