Exchange 2010 local server administrator password

The local administrator password on the Exchange 2010 Windows 2008 R2 server is unknown.  I'd like to change it (using Server Manager > Set Password function).  Is this going to adversely affect any of my Exchange operations?  I checked services and everything says it logs in as Network Service or Local System, nothing specifically lists a username.
fallriverelectricAsked:
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tshearonCommented:
It should not affect Exchange in any way.
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