Running 2008 R2 DC, windows 7 PC's. I had to create a GPO that added a setting in IE.. Tools\internet options\security\ intranet\ sites\advanced and it adds a couple of FQDN's.. For the most part we run IE 9 and the GPO worked on all of those PC's however we have a few PC's with IE 10-11 installed and on those PC's the setting doesnt get applied. When I do a GPresult it shows the GPO was applied to the PC. Is there an something extra I need to do that Im unaware of to get the GPO to work on IE10=11