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Server locking up every hour at same time

One of my clients has a server that freezes every hour at the same time.  I believe that when you reboot, whatever time the server comes up is the "magic time" wherein it then begins to lock up each hour.  For example- if the server completes its boot at 0938, it will then lock up at 1038, 1138, 1238 and so on.  All programs running from it lock up or disconnect entirely.  if working directly on the server the mouse moves, but no response from any click or key press.  The server is the only one on site- there are only four users.  Naturally it is the DC/DNS/DHCP.  It also hosts TrendMicro AV.  It used to host Spiceworks, but that has been removed.  There is absolutely nothing of any help in the Event Logs.  I've ran chkdsk and sfc (both of which found and repaired errors) but no change.  I assume it has to be a service or app, but I have no idea how to track it.
Windows Server 2003

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STS-Tech

8/22/2022 - Mon
Gary Fuqua, CISSP

Did you check scheduled tasks to see if anything is set to run every hour?
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Pramod Ubhe

first isolate the issue between software/ hardware, for that boot the server in safe mode and check if safe mode goes beyond 60min. if yes then it is definitely something related to software/OS, then you can check by disabling applications one by one in normal mode (start > run > msconfig > startup/services). for hardware issues it can be anything from a faulty hardware or driver or loose connections etc.
also see if you can analyze memorydump file located in c:\windows to see any issues or the root cause.
STS-Tech

ASKER
I have been running Process Monitor for a couple days and nothing jumps at me though it looks like lsass.exe takes as much processing power as the server has when it runs. Unfortunately, I am trying to troubleshoot a remote server so safe mode doesn't help.

This server also host Logics software and all that entails as well.

I am currently running Process Monitor and Process Explorer. Is there someone who is willing to take a closer look at any logs if I can post them? I've been staring at this problem for awhile now.
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William Peck
STS-Tech

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While none of the installed programs revealed the problem- they put us on the right path.  Turns out it was Trend Micro Admin Console