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Outlook 2010 "has stopped working" on New Email/Reply?

Hello all, we are experiencing a frustrating issue on all of our outlook clients (Outlook 2010 running on both Win 7 and 8).

A little bit of information to start, we recently moved from Exchange 2007 to 2013 (about a month ago) and had quite a few issues right away. We got most of these resolved and seem to have been running smoothly since then, but there are still a couple of things that we would like to get cleaned up as we can.

We have always used our clients in "cached exchange mode" and had no issues until after the migration, when we started noticing long delays in clients updating inboxes. (It will hang on "updating this folder..." in the bottom for 10-15 minutes before pulling mail into the inbox.)

As a workaround to this issue, we have tested the "online mode" (NOT cached exchange mode) which seems to completely resolve the delay issue. All messages display in the inbox instantly.

However, this "online mode" presents a new and more disabling issue: CLICKING SEND MAIL OR REPLY HANGS THE CLIENT FOR 3-4 MINUTES BEFORE OPENING THE WINDOW. If there is any input while it is hanging, the program will 'stop responding' and crash. If you are patient, after the window finally opens, then ANY SUBSEQUENT CLICKS OF NEW MAIL OR REPLY LAUNCH INSTANTLY.

The client will go on to work perfectly until it is restarted again, at which point the first attempt to compose a message will lock it up once more.

I checked the event logs and found a single very generic message from Windows Error Reporting about the hang:
Fault bucket , type 0
Event Name: AppHangTransient
Response: Not available
Cab Id: 0

Problem signature:
P2: 14.0.7113.5000
P3: 527d6330

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This happens on any PC in our office. I have tried rebuilding the outlook profile to no avail. I tried safe mode and no dice. Returning the client to cached exchange mode will solve the issue completely, but then we would be waiting 15 minutes to see mail.

I included the note about our server upgrade because I am fairly certain the issue is with the exchange configuration and not anything on the individual clients.
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1 Solution
Simon Butler (Sembee)ConsultantCommented:
This sounds like network issues connecting to the Exchange server.
Cached mode is actually push. Outlook sits there waiting for a packet from the server to say that something has changed, and then when it receives it goes and has a look.
However it will also look in the background on its own and of course if a user clicks on another folder, that will force a refresh.
The fact that you are seeing issues with live mode as well, suggests the problem is outside of Exchange. There is nothing in Exchange that can cause this.

I would be looking at anything common to all of the clients. I have seen security software (AV etc) cause these kinds of problems. I have also seen dodgy network cards, cables and switches cause the issue.
On the server itself, ensure that it is CU7 and any AV software has the correct exclusions on it. These are outlined in TechNet:

Exchange 2013 uses Outlook Anywhere to connect. Therefore if you have a proxy server in place, ensure there is a bypass for the Exchange URL configured in the clients.

BMFCAuthor Commented:
Thanks Simon for a pretty comprehensive first answer! Let me test a couple of these suggestions and I will let you know how it goes.
BMFCAuthor Commented:
Thanks again Simon! I actually found the solution to my issue on another EE thread, one that you yourself answered: here

In this case, I really wasn't specific enough about the method in which we migrated/then just did an unplug of exchange-old. The Public Folders were culprit.
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