I have been running ISA Server 2004 for many years without issue as a web proxy. Starting about a month ago, users are unable to get to a couple of specific websites:
I can get to them fine if I go directly out via my gateway, but if I go through the ISA, I get error:
Technical Information (for support personnel) •Error Code 10060: Connection timeout
•Background: The gateway could not receive a timely response from the website you are trying to access. This might indicate that the network is congested, or that the website is experiencing technical difficulties.
When I was first troubleshooting this, I blew away the urlcache (which had not been done in a very long time), and the problem was fixed. The issue is back again, and this time deleting the cache did not solve it.
These are the only 2 sites that are having this problem.