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Unable to get to specific websites via ISA Server proxy

I have been running ISA Server 2004 for many years without issue as a web proxy.  Starting about a month ago, users are unable to get to a couple of specific websites:

http://csllibrary.org/
http://www.cotesaintluc.org/en/welcomepage

I can get to them fine if I go directly out via my gateway, but if I go through the ISA, I get error:

Technical Information (for support personnel) •Error Code 10060: Connection timeout
•Background: The gateway could not receive a timely response from the website you are trying to access. This might indicate that the network is congested, or that the website is experiencing technical difficulties.

When I was first troubleshooting this, I blew away the urlcache (which had not been done in a very long time), and the problem was fixed.  The issue is back again, and this time deleting the cache did not solve it.

These are the only 2 sites that are having this problem.

Any ideas?

Thanks!
0
lor1974
Asked:
lor1974
1 Solution
 
bbaoIT ConsultantCommented:
ever tried accessing some other pages (rather than the homepages only) of the two sites especially those with basic HTML?

be aware that today is in 2015 and a 10+ years old web proxy server might not be able to understand all HTML coding nowadays.
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als315Commented:
There are many possible reasons for this error.
Check your NIC configuration according this article:
http://blog.msfirewall.org.uk/2008/06/isa-servers-recommeded-network-card.html

You can also try to increase timeout:
http://support.microsoft.com/kb/191143
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lor1974Author Commented:
I just increased the timeout in the registry.  I would have expected a reboot to be necessary before it would take, but before doing so I tested the sites and they are working now.  I guess it is just a coincidence.  We'll see if the sites stay working this time.

Thanks for the responses.
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