Changing Windows Server 2008 R2 Domain Admin Password

Recently had our main IT person left so we want to change the domain admin password.  We have one server in our environment, Server 2008R2.  We did some research on the impact and it looks like we need to double check any services/tasks that may be using the Admin account before changing the password.  So, we checked in Services and saw the backup software is using the Admin account.   Everything else listed is using Local System or Network Service.  Under Task Scheduler, we drill down to Task Scheduler Library, Microsoft, Windows, and see "Backup" running under the Admin account and nothing else.  Is there anything else we need to check for before changing the password?  And do we just log in as the admin and change it or is there another way it has to be done?  Thank you.