Why am I getting an Error 1309 : Error reading from file..... when attempting to use a .msi generated by InstallShield in VS 2013?

Error 1309 : Error reading from file.....

I am using VS2013 - with latest download of InstallShield Limited Edition

 From VS2013 -> Solution Explorer -> Installshield Project -> Uninstall/Install: everything is fine.

 If I run the installer file (right click .msi file->uninstall/install) from the directory it is compiled in everything is fine.

 If I copy the .msi file anywhere else I get the above error UNLESS I copy the 'program files' directory that is also created in the DISK1 folder of installshield project.

I thought this was all supposed to be packaged into 1 file (isn't that the purpose of InstallShield?)

This question was originally posted on the flexera forum, but no one seems to be responding
to questions on that forum:

https://community.flexerasoftware.com/showthread.php?214260-Error-1309-Error-reading-from-file

Any thoughts on how to fix this?

Thanks,
JB