I have a virtual Exchange 2007 box(VMWare VSphere 5.1, Windows 2008 R2, 2 processors, 12gb RAM) I have updated the server to SP3 in an effort to resolve the store.exe problem with no success. I have killed AV, I have moved all clients to Cached Mode after monitoring individual users with exmon. Still no success. Store.exe is still consuming almost all of the processor and memory. My server only has 60 mail boxes.