Autodiscover failed, how to get it resolved?

This is using 2 MS Exchange 2010 servers, 1 being the CAS, and another one is MB/Hub. Autodiscover used to work until probably 3 months ago. It was found not working as we have to resort to manual settings keyin instead of automatic configured. Both exchange servers using SP3

I checked the Microsoft remote test connectivity test, and the result is failed. Please see the results as attached.
The 2nd test is, I using Test Email Autoconfiguration, it also failed. 3rd test, browse to, and result with error - 600. But, other features - OWA, Outlookanywhere, and others are working fine. What could be the problem, and how to solve it?

thanks in advance.
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Patrick BogersDatacenter platform engineer LindowsCommented:

This is the URL that fails... starting with https (implying port 443 i would think) so try to browse to this URL with a browser and make some changes in the adress until it finds the right xml file.

This you need to adjust in exchange.

BTW: Http 600 means autodiscover service works so ignore that error.
MichaelBalackAuthor Commented:
Hi Patricksr 1972,

BTW, how to make the necessary changes in Exchange?
Patrick BogersDatacenter platform engineer LindowsCommented:
Hi Michael,

Via the exchange powershell module, for a step by step click this link.

look for
Get-ClientAccessServer |fl identity,autodiscoverserviceinternaluri
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MichaelBalackAuthor Commented:
Hi Patricksr1927,

The URL for autodiscover is present, nothing to change...
Patrick BogersDatacenter platform engineer LindowsCommented:
Ok, so what does outlook report when you test the service with only use autodiscover selected?
MichaelBalackAuthor Commented:
Hi Patricksr1972,

See my first article - attached testconnectivityresults.txt
Patrick BogersDatacenter platform engineer LindowsCommented:
Do you have a record in the DNS saying autodiscover?
Please rerun this test and uncheck the yellow marked options and show the log again.
MichaelBalackAuthor Commented:
Hi Patricksr1972,

In IIS > default web site; found multiple binding for 80/443. I have tidied them up with only a and *.
After that, it can passed the testconnectivity on autodiscover.

I'll arranged user to test the email configuration as mentioned

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MichaelBalackAuthor Commented:
The problem is on the IIS web site bindings. After the cleanup, autodiscover is working fine.
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