Is there a way to remove a particular email from Exchange? I have over 200 users that received a spam email that i want to remove from their Outlook

if you are using Exchange 2010 open Exchange PowerShell and execute following command;

get-mailbox | Search-Mailbox -SearchQuery ‘from:virussender@virus.com ‘ -TargetMailbox “adminmailbox” -TargetFolder “DeleteVirus” -LogLevel Full –DeleteContent

Regards,
Waddah

what is the adminmailbox? the target is everyone's mailbox and is the "DeleteVirus" a folder I need to create?

The admin mailbox is whatever mailbox name you put in there...it could be yours or a another persons. The target folder is the folder in which to put a copy of the deleted email in the admin mailbox specified... you don't need to do this... you could just -deletecontent but if the email hit is wrong you'd need a copy to put back!

The search query could also be the subject name - which is probably a better target...   i.e. -searchquery 'Subject:"Subject in here"'

the question here is the source is everyone and not a specific mailbox like an adminmailbox. Just confused.

Thanks guys!