Looking for helpdesk / service desk software

Hello,

I am looking for helpdesk or service desk software to replace Outlook.

It can be either a software package or "cloud based".

Requirements:
Exchange 2010 integration (if possible)
Different queues for different companies based on the domain
To be able to fill in time someone has worked on the ticket when closing it.
Customers should not receive any automatic confirmation e-mails from the help desk system
Direct reply from within the system. If possible with attachements.

Anyone have any recommendation?

Thank you.
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ItxxAsked:
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Andrew Hancock (VMware vExpert / EE MVE^2)VMware and Virtualization ConsultantCommented:
try Manage Engine Service Desk Plus Help Desk software.

its about the least expensive.

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