Polarity: Ibuprofen vs Acetanilide

Hello,
Comparing ibuprofen to acetanilide, which one would you expect to have a greater polarity? I've been reading that the alkyl group on ibuprofen would significantly reduce its polarity, and am wondering your guys' thoughts. Also, ibuprofen has a much lower solubility in water, but I don't know if that alone is enough to decide if it's more nonpolar.

Acetanilide:
Acetanilide.png
Ibuprofen:
Ibuprofen-racemic-2D-skeletal.png
stevedellAsked:
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ozoCommented:
The amide group is more polar than the carboxylic group, and acetanilide has a lower log P value than ibuprofen, which is also consistent with it being more soluble.
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stevedellAuthor Commented:
Hi ozo,
can you please explain the significance of the log P value?
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ozoCommented:
I found references for a log P value of 1.16 for acetanilide, and 1.27 to 1.37 for ibuprofen.
Lower values indicate more hydrophilic and more polar.
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stevedellAuthor Commented:
fantastic thank you ozo
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stevedellAuthor Commented:
thank you
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