Office 365 migration considerations

Hello All experts,
I am doing a project and my boss wants to explore if we can use the office 365 solution instead of our exchange 2010 solution
An organization with 5000 users, I would like to know why or why not should we choose O 365.

Thanks in advance....
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Cost would be one issue. 5000 users is $25,000-$30,000 per month. I'm not sure if MS discount for large volumes.
If all your users are in one place you'd want plenty of internet bandwidth as Office 365 would hammer your connection.
Migrating that many users to Office 365 would be a huge job.
On the other hand, your email hosting becomes Microsoft's problem.

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