Machine certificates for accessing a web app in IIS only from an specific PC client

We have an ASP.NET web app running in IIS, with about 200 users, some are inside our LAN and other ones are outside our LAN. Every user has a userid account and a password to login.

Besides those credentials, we want to add more security for accessing that web app with this requirement:

A user will access that web app just and only from its PC. If the user goes to other place and/or uses other PC, and even if its credential login were right, then he/she will not be able to access that web app.
We thought about using client-side certificates Now we are told that we can meet this requirement using machine certificates instead of client side certificates. With machine certificates, the user will not be able to use any other machine to use the web application.

Also we'd have to install a CA in our IIS server, but we can issue machine certificate for non Active Directory machines also.

Is it possible to meet this requirement with machine ceritificates?
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miyahiraAsked:
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David Johnson, CD, MVPOwnerCommented:
Yes you can add the CA role and yes non domain joined machines can request a certificate using the certificate enrolment site. you will not want users to get issued a certificate without some intervention at the CA
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