Server 2008 File Already in Use Error

I have searched for answers on this but so far haven't found anything which seemed pertinent. We are moving our redirected folders from Server 2003 to Server 2008. The users which have converted to the new server now get a message stating "[path/file] is already in use. Please try again later" when trying to save Office documents; more specifically it happens when they attempt a second save after saving it once.

Everything was set up the same on both servers - the folder permissions, share permissions, and caching settings. When we move the users redirects back to the 2003 server they can once again save their files.

This migration HAS to happen; am I missing some crucial difference between 2003 and 2008?  Is there some extra component of the  File Services role I need?

Edit - I have now noticed another symptom. When I go under "Manage Open Files" on the 2008 server I am seeing as many as 4 instances of the file being opened by the same user, plus the temporary file (~filename.xlsx). Hopefully this helps with an idea of what's happening.
JHMH IT StaffAsked:
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how long ago to you do the switch?  Is it possible files are still being copied over?
JHMH IT StaffAuthor Commented:
The copy process was halted before updating the GPO to move users to the new server.
assuming if you did that that you also did the gpupdate and gpresult ?
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JHMH IT StaffAuthor Commented:
Yes, users are certainly moving to the new server. The entire error displays as "'\\SERVER2\Redirects$\user\Desktop\Book1.xlsx' is currently in use. Try again later." If I change the GPO and move them back to SERVER1 (2003) the error does not occur.
what is the nic traffic on server looking like?
JHMH IT StaffAuthor Commented:
(FACE PALM)  It was our antivirus. On a whim I decided to see if it was the culprit - we're using SOPHOS Enterprise with vShield, and the second I uninstalled vShield from the 2008 server the file error went stopped occurring. However, our 2003 server has SOPHOS on it as a client (as opposed to vShield integration) and it works fine; at this point I'll be opening a ticket with SOPHOS to look for a resolution.

Thanks for your help, and hopefully this question and discovery the AV was causing the issue will help someone else in the future.

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that was going to be the next question.  great!
JHMH IT StaffAuthor Commented:
I was able to reinstall vShield, but I had to disable "on access scanning" completely. After the cryptoblocker attack we had a couple of months ago I'm not sure I want that disabled, so a support ticket to SOPHOS is the next step. Thanks again!
do you have exes blocked in appdata?
JHMH IT StaffAuthor Commented:
Yes, we have the full Cryptoblocker Prevention Kit from Spiceworks implemented - but somehow one got through. We have since updated and re-enforced the policies and they seem to be working well - we have to move computers to the "Computers" container (which doesn't apply the the settings) just to install software. But as we all know, the bad guys are constantly looking for new ways around our security and apparently whoever crafted the attack which made it through found one.
Seth SimmonsSr. Systems AdministratorCommented:
This question has been classified as abandoned and is closed as part of the Cleanup Program. See the recommendation for more details.
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Windows Server 2008

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