VB.net Replace text in body of email before Send

I use the following VB.net code to use a Word document as the body of an Outlook email.
I want to call this code several times, replacing various text in the Outlook body with
other text. What code would I use to replace text in the Outlook Body (not the Word doc)
just before the email is sent?

    Public Sub SendDocAsMsg()

        Dim wd As Microsoft.Office.Interop.Word.Application
        Dim doc As Microsoft.Office.Interop.Word.Document
        Dim itm As Microsoft.Office.Interop.Outlook.MailItem
        Dim ID As String
        Dim blnWeOpenedWord As Boolean

        'wd = CreateObject("Word.Application")
        wd = New Microsoft.Office.Interop.Word.Application
        wd.Visible = True

        Dim oFilePathName As String = "C:\Users\Documents\Test.docx"

        doc = wd.Documents.Open(FileName:=oFilePathName, ReadOnly:=True)

        itm = doc.MailEnvelope.Item
        With itm
            .To = "murbro933@yahoo.com"
            .Subject = "VVV Subject"

        End With


        doc = Nothing
        itm = Nothing
        wd = Nothing

    End Sub
Murray BrownMicrosoft Cloud Azure/Excel Solution DeveloperAsked:
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Alter code a bit like this:

   With itm
             .Body = .Body.Replace("this","to that") 'or if syntax isn't correct .Body = Strings.Replace(.Body, "this", "to that")
             .To = "murbro933@yahoo.com"
             .Subject = "VVV Subject"

         End With

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Murray BrownMicrosoft Cloud Azure/Excel Solution DeveloperAuthor Commented:
Thanks very much
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Visual Basic.NET

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