VBA replace too long to run

My code is taking too long to run on a large data set.
Can someone help improve by making it more efficient?
All it does is look for errors in either u,v,w or x and delete the row.
First it is 'trimming', because it was not recognizing errors at all, until I used the trim characters.
I appreciate any help!

Sub delerrors()
Application.ScreenUpdating = False
Reduced_Data.Activate


    Dim i As Long
    i = 2
    Do Until i > Cells(Cells.Rows.Count, "A").End(xlUp).Row
        If Replace(Cells(i, "u").Text, Chr(32), "") = "#REF!" Or _
           Replace(Cells(i, "u").Text, Chr(32), "") = "#N/A" Or _
           Replace(Cells(i, "v").Text, Chr(32), "") = "#REF!" Or _
           Replace(Cells(i, "v").Text, Chr(32), "") = "#N/A" Or _
           Replace(Cells(i, "w").Text, Chr(32), "") = "#REF!" Or _
           Replace(Cells(i, "w").Text, Chr(32), "") = "#N/A" Or _
           Replace(Cells(i, "x").Text, Chr(32), "") = "#REF!" Or _
           Replace(Cells(i, "x").Text, Chr(32), "") = "#N/A" Then
            Rows(i).Delete
        Else
            i = i + 1
        End If
    Loop
End Sub

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