What parts of the Windows 7 system subfolders can safely be deleted?

I am running out of space on my C: drive on my Windows 7 machine and using JDiskReport to analyse where the storage is being used I find these big ones:

C:\Windows\assembly 3.7GB
C:\Windows\Installer: 9.6GB
C:\Windows\System32: 10.4GB
C:\Windows\winsxs: 24.5GB (of which "Other" is 21.8GB)

C:\Users\All Users\Package Cache: 5.4GB (most in "Other")

Are any of those targets for either deletion or some form of cleanup?

Is there a utility that could get rid of anything *really* not necessary (and that won't break my system)?
KhaiPiAsked:
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David Johnson, CD, MVPOwnerCommented:
run up the disk cleanup manager and select cleanup system files
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KhaiPiAuthor Commented:
I tried that and it only reported 186MB of files that it could clean-up which would hardly even make a dent.
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rindiCommented:
Use the Cleanup utility to free up space (right click "Computer", select "Manage", then "Disk Management", right click the partition you have the OS on, select "Properties", and in the "General" tab click on "DiskCleanup".

Besides that you can also make just a small pagefile on C: (about 256MB is enough, and a system managed one on D:.

Delete the contents of C:\Windows\SoftwareDistribution\Downloads.

disable hibernation (open an elevated cmd prompt and enter powercfg -h off).
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David Johnson, CD, MVPOwnerCommented:
you've already moved your documents/music/pictures/videos to another drive?
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KhaiPiAuthor Commented:
Yes David, I have all of those on my D: drive.
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McKnifeCommented:
KhaiPi, I am pretty sure you did not follow David's advice to the T. When in disk cleanup, did you click on the button "clean up system files"? Then, you would have had more options and the GBs will fall.
The system files cleanup option was added with a patch, see whether you have it installed: https://support.microsoft.com/en-us/kb/2852386
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KhaiPiAuthor Commented:
I was initially confused by which disk cleanup tool to use but the three selected solutions combined enabled me to reclaim quite a bit of disk space.

Thanks very much!
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