I am having an issue with a new 2012 R2 Server That drops off of the network every morning due to an error.

This is the error that I am receiving on this server.
1. The firewall is turned off
2. this server is an application server that communicates with its clients using NTLM (Kerberos is not supported)
3. This server is hosted on ESXi server and is a Vsphere client (most recent update) for both.
4. This server is not running an anti-virus client at this time.
5. IPV6 is disabled

here is the article that best describes the problem I am having: https://social.technet.microsoft.com/Forums/en-US/7c3795c6-e8e6-4923-bc3f-c683ae05c598/unable-to-update-the-ip-address-on-isatap-interface-isatapxxxxxxxxxxxx-update-type-1-error?forum=winservergen 

Exact error I am seeing: "Unable to update the IP address on Isatap interface isatap.{EC4C5462-78B8-48DC-846C-5E359DE14F39}. Update Type: 1. Error Code: 0x490."

Thank you,
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Andrew Hancock (VMware vExpert / EE MVE^2)VMware and Virtualization ConsultantCommented:
Make sure you are using the VMXNET3 interface, and not the E1000, and you have VMware Tools installed, to support the VMXNET3 interface.

Also make sure you are using a unique IP Address and MAC Address, and there are no conflicts here.

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Zac HarrisSystems Administrator Commented:
A possible solution would be to uninstall the ISATAP Adapter and the Teredo Tunneling Pseudo-Interface. As long as you are not using IPv6 there should be no negative impact on your machine.

Some background on the Teredo Tunneling Pseudo-Interface if you need it:

The Teredo tunneling is a method of tunneling IPV6 traffic over an IPV4 network.
There are lots of issues with it so it is best to make your network 100% IPV6 or 100% IPV4.
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Windows Server 2012

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