I.T. guys having problems at work today, thought I would tell you the problem to see if you can make my suggestions tomorrow look intelligent.
Windows 2008r2 VM running on ESXi4.0. After it starts and an admin tries to log in it hangs on "Please wait for the user profile service" with a rotating wait icon.
In this state can not obtain an Remote Desktop Connection.
When restarted in Safe Mode with Networking Admin can log in.