I have a Windows File Server 2012 R2 with network shares. I am having an issue with Microsoft Office, excel, word, etc. coming up with a message on random files (see attached). I have gone into Computer Management, shared folders and it does not show the file open. I can open the files with another program such as notepad and it works fine. The only way I have found to fix this issue is to restart the file server. It doesn't matter what version of Office I use.
I tried using a program such as Unlocker and it says, "No Locking handle found."