File Server 2012 R2 File in Use

I have a Windows File Server 2012 R2 with network shares.  I am having an issue with Microsoft Office, excel, word, etc. coming up with a message on random files (see attached).  I have gone into Computer Management, shared folders and it does not show the file open.  I can open the files with another program such as notepad and it works fine.  The only way I have found to fix this issue is to restart the file server.  It doesn't matter what version of Office I use.

I tried using a program such as Unlocker and it says, "No Locking handle found."

Any thoughts?
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unless i am mistaken, the attachments were not saved...
ollybubaAuthor Commented:
See attached.
Davis McCarnOwnerCommented:
What O/S is running on the workstations and do you have all of the updates installed?
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Tony GiangrecoCommented:
That message means a user has that file open in Excel or they had it open and closed excel but that workstation didn't release the file. The best way to resolve this issue is to check Administrator Tools/Computer Management/Shared Folders/open files and look for a user listed with that file name.

If you still can't find it, restart the workstations to release the lock.
btanExec ConsultantCommented:
The link has been handy in listing the various scenario this can pop up and most of the feedback shared likely due to Explorer and its Preview Pane so it need to "unchecked"
In a Windows Explorer window, do the following:

1. Right click on the Start Button.
2. Click 'Open Windows Explorer'.
3. At the top left click Organize > Layout
4. Uncheck Details Pane and Preview Pane.
5. On a Windows menu, click on Tools > Folder Options. In the box that opens up, click on the View tab. Scroll down the list to “Show pop-up description for folder and desktop items” and clear the checkbox and then click OK.

In Excel:

1. Click File > Open
2. Click Organize > Layout
3. Uncheck 'Details Pane' and 'Preview Pane'

If Outlook is involved:

1. Open a new e-mail.
2. In the "Include" group, click Attach File.
3. Click Organize > Layout
4. Uncheck 'Details Pane' and 'Preview Pane'.
Jim Dettman (Microsoft MVP/ EE MVE)President / OwnerCommented:
One gotcha here is users using Explorer with the preview pane turned on.

As far as the server is concerned, this is "in use" even though the file is not actually opened in Office.

Jim Dettman (Microsoft MVP/ EE MVE)President / OwnerCommented:
Oops, see someone already posted that.  Sorry.

ollybubaAuthor Commented:
The server is running Windows Server 2012 R2 and the workstations are all 7 Pro.  All updates are installed.  I have looked at open files on the server and it does not list it as being open.  The other thing is it says it is locked by 'another user'.  How do I know which workstation to restart?  The preview pane is also not being used on any of the computers.
btanExec ConsultantCommented:
another means is to try on client and server to further confirm by using Sysinternal Process Explorer, go to Find->Find Handle or DLL. In the "Handle or DLL substring:" text box, type the path to the file (e.g. "C:\path\to\file.txt") and click "Search". All processes which have an open handle to that file should be listed. If exist, you click on an entry to focus on that process in the main window. You can then even close the handle manually through the lower pane. Another tool is LockHunter

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ollybubaAuthor Commented:
I am currently waiting for a file to become locked again.  Sorry for the delay in responding to your response.
btanExec ConsultantCommented:
thanks for update
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Windows Server 2012

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