Exchange smarthost in DMZ - what ports to open up?

I've got a Proofpoint appliance setup and IP for it is in the DMZ.
I am wondering besides the ports needed open on the Proofpoint appliance (as far as connecting to management console from an internal IP), are there typically other ports/connections that need to be allowed between the smarthost in the DMZ and the internal Exchange servers? Exchange 2010 and 2007 mix is environment I have.
garryshapeAsked:
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StuartTechnical Architect - CloudCommented:
Port 25 and 587 should be sufficient for mail flow, Does the appliance use AD integrated logins OR LDAP based group queries if so TCP/UDP 389 , 88, 53 etc

Where will the server get its time source from,

You really need to understand the features of the product and more importantly which ones you will use, I suggest you ask proofpoint for a architecture diagram which details the ports utalized by the appliance

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garryshapeAuthor Commented:
That makes sense, and yes, working to get confirmation on appliance info. It's been a bit fragmented and networking person has been gone mostly :(
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