Information Store Service on Exchange 2010 is not starting

My Exchange 2010 server Information Store Service is not starting and I get the below error on the windows Event log.

Active Manager failed to mount database Mailbox Database 0332199996 on server BDTD.sadr.local. Error: An Active Manager operation failed with a transient error. Please retry the operation. Error: Database action failed with transient error. Error: A transient error occurred during a database operation. Error: MapiExceptionNetworkError: Unable to make admin interface connection to server. (hr=0x80040115, ec=-2147221227)

I already rebooted it and tried but not working. This is also a Vm.

Please help
Who is Participating?

[Product update] Infrastructure Analysis Tool is now available with Business Accounts.Learn More

I wear a lot of hats...

"The solutions and answers provided on Experts Exchange have been extremely helpful to me over the last few years. I wear a lot of hats - Developer, Database Administrator, Help Desk, etc., so I know a lot of things but not a lot about one thing. Experts Exchange gives me answers from people who do know a lot about one thing, in a easy to use platform." -Todd S.

Muhammad BurhanManager I.T.Commented:
Shweta GoelCommented:

•      Synchronize time with DC and then try to start it.
•      Forefront should be disable
•      Try to increase time out value for Exchange Server store service and then try.

Check the NIC settings, it all settings are fine.
Creating Active Directory Users from a Text File

If your organization has a need to mass-create AD user accounts, watch this video to see how its done without the need for scripting or other unnecessary complexities.

MASEE Solution Guide - Technical Dept HeadCommented:
Agree with Gaurav
Please check the NIC settings first.
moeshakirAuthor Commented:
NIC settings look normal
MASEE Solution Guide - Technical Dept HeadCommented:
moeshakirAuthor Commented:
I tried em all and nothing works.
This started happening after the "Update Rollup 10 for exchange server 2010 sp3 installed" 2 days ago.
Senior IT System EngineerIT ProfessionalCommented:
Try installing "Update Rollup 11 For Exchange 2010 SP3 (KB3078674)"

This should fix Information Store service crashes randomly in an Exchange Server 2010 environment.
moeshakirAuthor Commented:
Finally I was able to fix the issue. It was the AV. Below are the steps I did.

Click Start, and then click Run.
In the Open box, type regedit, and then click OK.
In Registry Editor, locate the following subkey in the registry:
In the right pane, double-click Enabled.
Click Decimal, type 0 in the Value data box, and then click OK.
On the File menu, click Exit to quit Registry Editor.
Start the Information Store.

Experts Exchange Solution brought to you by

Your issues matter to us.

Facing a tech roadblock? Get the help and guidance you need from experienced professionals who care. Ask your question anytime, anywhere, with no hassle.

Start your 7-day free trial
MASEE Solution Guide - Technical Dept HeadCommented:
Thanks for sharing the solution.
Appreciate if you mention antivirus name.
moeshakirAuthor Commented:
Microsoft Forefront Protection 2010 for Exchange Server
moeshakirAuthor Commented:
I was able to fix it
It's more than this solution.Get answers and train to solve all your tech problems - anytime, anywhere.Try it for free Edge Out The Competitionfor your dream job with proven skills and certifications.Get started today Stand Outas the employee with proven skills.Start learning today for free Move Your Career Forwardwith certification training in the latest technologies.Start your trial today

From novice to tech pro — start learning today.