We are currently unable to turn on out of office in both outlook and OWA. In outlook I am getting the "You automatic reply settings cannot be displayed because the server is currently unavailable" I did the autoconfiguration test and there were no errors. It was working. I recently was trying to get HTTPS redirection working, and I changed the URL in the default website and the error pages, but I have changed these settings back with no success. I tried entering the OOF URL from the test results and it doesn't seem to resolve. I believe it may be an IIS issue? We are currently running Exchange 2010 on a Server 2012 R2 box and 2013 clients.