How can I apply a Group Policy to all users except the administrator and only on specified computers?

Thomas -
   Thank you.  That was helpful.  I see how to specify all Server 2008 R2 computers, but how would I specify all users that aren't administrator?

If I put the groups "User List 1" and "Computer List 1" in Security Filtering, will the GPO :

1.) only be applied to a User from "User LIst 1" logging into a computer from "Computer List 1"

or

2.) be applied whenever a user from "User List 1" logs into any computer and whenever any user logs into a computer from "Computer List 1"

or

3.) the computer settings will be applied to any computer in "Computer List 1" and the user settings will be applied to any user in "User List 1"

That last post was a separate question.  Sorry if that made it confusing.  To answer your question, I want to just exclude the administrator, but don't want to manually create and maintain a group of every user that isn't an administrator.  Is there a way to create a group for "every user but administrator" (i.e. instead of specifying every user that belongs to the group, specify the one user that doesn't belong to the group)?  Or would I do that in a select statement via WMI?

administrator is a member of "domain users".  Are you recommending that I delete administrator from this group?  And are you also recommending that any user in the "Domain Admins" group be removed from the "domain users" group?

What would the WMI select statement be to select all users but administrator?

Also, I only want to apply *user settings* to Server 2008  computers (and only if the user isn't administrator).  If user filtering is for user setting and computer filtering is for computer settings, I still don't understand how I could make this work.  Is it possible?