Permission errors on one file causing app to crash

For some reason one .exe file permissions were removed and I can't delete the file, change permissions, or take ownership.

Obviously the app won't run like this.

Admin account I'm using has admin, domain admin, enterprise admin, and schema admin permissions and still can't take ownership of the file. Goal, provide permissions for app to work or delete. Currently can't restore to overwrite the file with permission errors.

Any ideas how to resolve?
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WORKS2011Austin Tech CompanyAsked:
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Toni UranjekConsultant/TrainerCommented:
Use icacls to take ownership and/or rewrite permissions:
https://technet.microsoft.com/en-us/library/cc753525.aspx
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WORKS2011Austin Tech CompanyAuthor Commented:
Server restart caused the locked out file to delete during reboot. I restored from backup and everything is fine now. I don't like to restart during business hours however this is a business critical app.

Toni I didn't get to look into the above link but thank you for replying.
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WORKS2011Austin Tech CompanyAuthor Commented:
server restart fixed the issue, see previous comment
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Windows Server 2008

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