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Can you telnet to the smart host on port 25 from the Exchange server?<br />
&nbsp;If so, restart the transport service on the server
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Can you telnet to the smart host on port 25 from the Exchange server?
 If so, restart the transport service on the server

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I cannot and was just called back by our provider to inform me they're having issues.
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I cannot and was just called back by our provider to inform me they're having issues.

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There is your problem Chris!!!
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Turned out to be an isp issue and not a server issue.
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Turned out to be an isp issue and not a server issue.

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All of the sudden after about midnight last night all outgoing mail is stuck in our queue. Nothing was changed on the receive and send connectors. When going through telnet on the mail server I am getting 550 5.7.1 unable to relay, this is to external addresses. We relay all mail via smarthost and I have confirmed with them that everything is fine on their end.<br />
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I have checked under &quot;Server Configuration&quot; mail server properties and the mail server is set to use the NIC's DNS for external DNS. I really do not know where to go from here.
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All of the sudden after about midnight last night all outgoing mail is stuck in our queue. Nothing was changed on the receive and send connectors. When going through telnet on the mail server I am getting 550 5.7.1 unable to relay, this is to external addresses. We relay all mail via smarthost and I have confirmed with them that everything is fine on their end.

I have checked under "Server Configuration" mail server properties and the mail server is set to use the NIC's DNS for external DNS. I really do not know where to go from here.

Exchange 2010 all mail stuck in queue

Exchange is the server side of a collaborative application product that is part of the Microsoft Server infrastructure. Exchange's major features include email, calendaring, contacts and tasks, support for mobile and web-based access to information, and support for data storage.