Is there a way to use GPO to update the default access of a folder on company PCs?

I would like to set up a GPO to update the access level of a particular folder on company PCs so that the owner of the folder is the only one that can access that folder.
I am running Win 2012 r2 DC and Win 7 PCs.

Can this be done with GPOs?

Thank you,
John WaterAsked:
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Muhammad BurhanManager I.T.Commented:
we have to set NTFS/SMB permissions on the folders manually, because how the file system come to know about the owners.

enable enumeration on shares and set NTFS permissions so other users not even see unwanted folders
FOXActive Directory/Exchange EngineerCommented:
swfwmd2,
Log in to the 2012 server where the folder is.  Go to Server Manager>Roles(expand roles)>File Services(expand)>highlight Share and Storage Management.  Highlight your share then click properties on the right side. Click the permissions tab, then share permissions button.  For the groups or users you don't want access to the share-clear their allowed rights and you can actually deny their rights, allow rights to only the user or owner you want.
John WaterAuthor Commented:
Since we were wanting to update access to consistently named folder on all of our user's PC, we created a GPO Windows settings\Security Settings\File Systems then entered the folder name and gave the desired permissions.

This has worked in testing and we will proceed with full implementation in the near future.

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John WaterAuthor Commented:
This was the best, most complete solution for our issue
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Windows Server 2012

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