configure SQL Server 2008 R2 to send external email

I finally got SQL Server configured so that I could send emails to users on my domain from within a stored procedure using msdb.dbo.sp_send_dbmail

but I'm currently unable to use this method to send messages to external email addresses (those outside my domain).  When I attempt to send outside my domain, I get the following error message:

The mail could not be sent to the recipients because of the mail server failure. (Sending Mail using Account 1 (2015-10-30T10:00:25). Exception Message: Cannot send mails to mail server. (Mailbox unavailable. The server response was: 5.7.1 Unable to relay).
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Dale FyeAsked:
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Dale FyeAuthor Commented:
BTW,  in another post, someone indicated that there is an Exchange setting which needs to be changed, but he was unsure what the setting was, and what the appropriate value is.
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ste5anSenior DeveloperCommented:
You need to enable relaying. This depends on your Exchange version.

Exchange 2010 - Allow Anonymous Relay on a Receive Connector
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arnoldCommented:
Are you using the local iis console 6 SMTP or are you telling SQL to use a remote SMTP server to send through?
Using the local provides the option that is under your control and has few issues.
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Dale FyeAuthor Commented:
Thanks for your assistance.
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Microsoft SQL Server 2008

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