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Do you mean within your desktop (say, MS-Windows operating system) environment, relative to your physical screen dimensions, or within the main application window of the MS-Excel application?
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Do you mean within your desktop (say, MS-Windows operating system) environment, relative to your physical screen dimensions, or within the main application window of the MS-Excel application?

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Within the Operating System desktop.
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You can set the application's window coordinates with VBA, triggered by opening the workbook. However, that repositions the whoel Excel window, even if it contains other workbooks.
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You can set the application's window coordinates with VBA, triggered by opening the workbook. However, that repositions the whoel Excel window, even if it contains other workbooks.

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I've requested that this question be deleted for the following reason:<br />
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Not enough information to confirm an answer.
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I've requested that this question be deleted for the following reason:

Not enough information to confirm an answer.

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John, your suggestion is simple and obviously works best. &nbsp;<br />
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Sorry this took so long. &nbsp;Aerovacced in the middle of the night for a 3-way bypass that was a misdiagnosis that turn into more and more complication.<br />
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Alas, &quot;You cannot kill a man born to hang!&quot;
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John, your suggestion is simple and obviously works best.  

Sorry this took so long.  Aerovacced in the middle of the night for a 3-way bypass that was a misdiagnosis that turn into more and more complication.

Alas, "You cannot kill a man born to hang!"

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Can you configure spreadsheets in Excel where they open in a particular position and window size?
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Can you configure spreadsheets in Excel where they open in a particular position and window size?

Opening position of a spreadsheet in Excel 2013

Microsoft Excel topics include formulas, formatting, VBA macros and user-defined functions, and everything else related to the spreadsheet user interface, including error messages.

Microsoft Excel

A spreadsheet is an interactive computer application program for organization, analysis and storage of data in tabular form. Spreadsheets developed as computerized simulations of paper accounting worksheets. The program operates on data represented as cells of an array, organized in rows and columns. Each cell of the array may contain either numeric or text data, or the results of formulas that automatically calculate and display a value based on the contents of other cells.

Spreadsheets

Visual Basic for Applications (VBA) enables building user-defined functions (UDFs), automating processes and accessing Windows API and other low-level functionality through dynamic-link libraries (DLLs). VBA is closely related to Visual Basic and uses the Visual Basic Runtime Library, but it can normally only run code within a host application rather than as a standalone program. It can, however, be used to control one application from another via OLE Automation. VBA is built into most Microsoft Office applications.