Windows 7 won't respond to mouse clicks until Task Manager is started.

Gateway SX 2802, Windows 7 Home Premium, Pentium Dual Core, 6 GB RAM, 64 Bit.

There are times when the system doesn't respond to mouse clicks on task bar, and most noticeably when gMail is being read on Chrome.
I can get a response from clicks if I ctrl-alt-del  and start Task Manager.  Something about that procedure seems to get the computer responding again.
No problems with keyboard.  If clicking on gmail in Chrome doesn't work, I can still Alt-Tab to other programs.

Can't figure out what's damaged.

All MS updates have been installed.
I ran AdwCleaner and RogueKiller, which found some things, including a Chrome extension that I removed.
MalwareBytes and Microsoft Security Essentials are installed.

Who is Participating?

[Product update] Infrastructure Analysis Tool is now available with Business Accounts.Learn More

I wear a lot of hats...

"The solutions and answers provided on Experts Exchange have been extremely helpful to me over the last few years. I wear a lot of hats - Developer, Database Administrator, Help Desk, etc., so I know a lot of things but not a lot about one thing. Experts Exchange gives me answers from people who do know a lot about one thing, in a easy to use platform." -Todd S.

do  a system restore to a date it was ok

Experts Exchange Solution brought to you by

Your issues matter to us.

Facing a tech roadblock? Get the help and guidance you need from experienced professionals who care. Ask your question anytime, anywhere, with no hassle.

Start your 7-day free trial
Jackie ManIT ManagerCommented:
What is your spec regarding HDD, Network card, Video Card?

How many tabs you have opened in Chrome?

How full is your HDD?
or take a backup - and do a fresh install
you can also use the factory restore partion - or media
It's more than this solution.Get answers and train to solve all your tech problems - anytime, anywhere.Try it for free Edge Out The Competitionfor your dream job with proven skills and certifications.Get started today Stand Outas the employee with proven skills.Start learning today for free Move Your Career Forwardwith certification training in the latest technologies.Start your trial today
Windows 7

From novice to tech pro — start learning today.