exchange 2013 cu7 getting a good amount of spam

We are running Exchange 2013 cu7. We have the malware agent disabled because it causes connection issues with some devices on the network. we have the ipblocklist provider and ipblocklist entry enabled but spam still seems to get in through the list of blocked ip addresses.
We also have symantec mail security installed and still we get certain spam over and over, 2 at a time. Does anyone have any suggestions on  what i can do to resolve this.

There is spam being blocked but something is letting these through even though i have blocked the ip from which they come from.
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Scott CSenior EngineerCommented:
We use McAfee at our company and for our customers.

So far I personally have not had a spam email come to me.

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