Debugging web page; net::ERR_INSECURE_RESPONSE

I have a web page the opens in a window via JavaScript.  I've spent a lot of time debugging without much success.  I do see the following error when I go into Developer Tools for that window (in Chrome):

GET https://localhost:44399/505266b2c97b422994d16354c880340c/browserLink net::ERR_INSECURE_RESPONSE

I am wondering what I might focus on in order to resolve this?
Tom KnowltonWeb developerAsked:
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From the message it seems that you trying to access something across servers, which is not allowed in browsers. But can you give more details?

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