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please clarify if you are using Server 2012R2 with Essentials Experience or Server 2012R2 Essentials. 
Are both domains in the same forest? 
AFAIK, you have to use the Exchange DC for Exchange access with an accepted domain of the WS2K12E domain 
 

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The SBS/Essentials server must hold all of the Flexible Single Master Operations (FSMO) roles. While promoting additional domain controllers is permitted, transferring any of these roles to one of them is not. 
There can be only one domain in the forest containing the SBS/Essentials server, as trusts between domains are not permitted. This includes parent-child trusts. Therefore, child domains cannot be created in an SBS/Essentials environment. In short, additional domain controllers are OK; additional domains are not. 
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<a href="http://www.dell.com/support/article/us/en/04/SLN288459/EN" rel="ugc nofollow">http://www.dell.com/support/article/us/en/04/SLN288459/EN</a>
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David 
Thanks for the quick response! 
 
Server 2012 R2 with Essentials Experience on a VM that's also the primary DNS and only DC 
Exchange is on another VM. 
 
They both belong to the same AD &nbsp;ad.mydomain.net and both have SAN WildCard Certs for mydomain.net, .org, .com 
 
mydomain.net, and .com all point to the the external IP as well as mail.mydomain.org. 
 
All services work correctly from inside the network. 
Services on either VM work correctly when forwarded directly from the router. However, since essentials and exchange webapp both need 80 and 443 I need to designate one to forward/rewrite &nbsp;one FQDM to the other VM after receiving it from the router. The method that is recommended is url rewrite and ARR. I have entered that on the exchange VM for the mydomain.net and it works. Essentials is available and can be logged into. But when I try to access a device by pressing the name or icon in the panel nothing happens. When the server is accessed directly through the router or from within the network it opens a dialog that offers to connect you via webapp remote desktop. 
 
Im guessing its some kind of a port or dns issue but I have no idea where to look. The java script that executes the remote desktop app is breaking here. 
 

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error SCRIPT5009: 'Microsoft' is undefined 
 
function tryLaunchRdp(hostname,userName,doesUseCookieBasedAuthentication,processAjaxRequestUrl,onStart,onComplete,requireRDP7,applicationPath,isDashboard){if(!svc){svc=new Microsoft.WindowsServerSolutions.Web.RDP.IRemoteDesktopWebService();} 

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That sounds like there was a connection that isnt being made earlier and failing when the script calls upon an unset object. This is madening because ITS SO CLOSE!!
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**** NOTE the solution I wrote above does not permit me to edit the text. The use of the word &quot;header&quot; &nbsp;should be 'handler' I didn't catch this mix up until I went back over the text some days later. ****** 
 
&nbsp; &nbsp;This solution was a bit difficult to hunt down. I finally ran some developer diagnostics from the browser to find what I suspected was happening. &nbsp;That's kind of like looking at the tailpipe to figure out why the motor is not starting. Although the issue was a configuration issue Its not really covered in any tech note I could find. What I did find was a small note over at server fault about a similar issue that made my issue clear. This will happen to everyone who needs to configure a single external ip with url rewrite. Because there are other services handled in this way this may also give someone else a clue where to look for non functioning / missing content.
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I have 2 domains coming to a single ip address. I use one for exchange and one for essentials. 
&nbsp; &nbsp; &nbsp; &nbsp;exchange 2013 is running &nbsp;on 1 vm with a split dns record and a url rewrite entry for the domain for ports 80 and 443 
&nbsp; &nbsp; &nbsp; &nbsp;Another vm with the DC running essentials experience. 
 
My router forwards 80 and 443 and most other ports to the exchange server 
 
When I try to reach 2012 R2 Essentials Remote Web Access &nbsp;I can log in, the email app works but when I try to remote to a device nothing happens. No popup or any message. 
 
If I point 80 and 443 to the DC with essentials experience the device access works fine but no webmail. 
If I also add a rewrite to the DC for exchange VM the webmail comes up, sends and receives but, no contact info and it wont display any of the email contents except the first entry displayed when I login. If you highlight another message the display window shows &quot;Error currently unavailable.&quot; 
 
How do I fix this?
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I have 2 domains coming to a single ip address. I use one for exchange and one for essentials.
       exchange 2013 is running  on 1 vm with a split dns record and a url rewrite entry for the domain for ports 80 and 443
       Another vm with the DC running essentials experience.

My router forwards 80 and 443 and most other ports to the exchange server

When I try to reach 2012 R2 Essentials Remote Web Access  I can log in, the email app works but when I try to remote to a device nothing happens. No popup or any message.

If I point 80 and 443 to the DC with essentials experience the device access works fine but no webmail.
If I also add a rewrite to the DC for exchange VM the webmail comes up, sends and receives but, no contact info and it wont display any of the email contents except the first entry displayed when I login. If you highlight another message the display window shows "Error currently unavailable."

How do I fix this?

Essencials experience and exchange 2013 not playing nice

IIS is Internet Information Services, the web server included with Windows Server operating systems. All current versions are built on a modular architecture; modules can be added or removed individually so that those required for specific functionality are installed. The full installation of IIS includes HTTP, security, content, compression, caching, logging and diagnostics.

Microsoft IIS Web Server

Exchange is the server side of a collaborative application product that is part of the Microsoft Server infrastructure. Exchange's major features include email, calendaring, contacts and tasks, support for mobile and web-based access to information, and support for data storage.

Exchange

HTTPS is a protocol for secure communication over a computer network which is widely used on the Internet. HTTPS consists of communication over Hypertext Transfer Protocol (HTTP) within a connection encrypted by Transport Layer Security (TLS) or its predecessor, Secure Sockets Layer (SSL). The main motivation for HTTPS is authentication of the visited website and to protect the privacy and integrity of the exchanged data. HTTPS is widely used for protecting page authenticity on all types of websites, securing accounts and keeping user communications, identity and web browsing private.

SSL / HTTPS

The Domain Name System (DNS) is a hierarchical, globally distributed system responsible for associating the name of a computer, service or other resource into an IP address for connecting to the Internet or a private network. Most prominently, it translates domain names to the numerical IP addresses needed for the purpose of computer services and devices worldwide.