Zoho vs Salesforce

We are trying to decide to go with Zoho or Salesforce. Zoho is pennies compared to the estimate from Salesforce. My big question is-- is Zoho adequate enough?

If we go with Zoho, we will be partnering with programmer who will be build some custom modification for us. Other than a few modifications, we do not have very many unique needs.

Any input to experience with either would be great. Thanks!