Prevent Office 365 Users from Setting up Outlook E-mail

Would like to know if it is possible to restrict the ability of Office 365 / Exchange 365 users from downloading their entire mailbox through the Outlook client (Office suite of applications) to only a whitelisted IP addresses (for example corporate networks).

Meaning users could only retrieve e-mail from Outlook web via Office 365 or ActiveSync.
Rammy CharlesSales EngineerAsked:
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Vasil Michev (MVP)Commented:
If you have AD FS in place, you can use claims rules to restrict access to specific addresses only. Otherwise you can disable the MAPI protocol for said users via Set-CasMailbox.
Rammy CharlesSales EngineerAuthor Commented:
No ADFS but would like to restrict MAPI but only to a specific IP (is that possible)? For example, our corporate LANs and whitelist those IPs so that only MAPI connections from there would be allowed.
Vasil Michev (MVP)Commented:
Not really, Office 365 being a public cloud service is by definition accessible from any location. You can try using Azure MFA as a workaround, as it does offer a whitelist functionality, but that doesnt apply to only Exchange and you will have to use even uglier workarounds after...

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