Update Panels with Gridview

I want to add an UpdatePanel to update my gridview. I have a couple of spots that I want the gridview to be updated but Im not sure how to go about adding in and setting it up. I have added a pic of a part of my app where I want the update panel to be used.... When I hit the Upload button I want the gridview procedure to run and bind my data to the gridview without the whole page posting back. I also want the same thing to happen when I click on the radio buttons(Handbook and Acknowlegement).
Can someone please help me with this. Along with my pic I have the code for my markup so you can see where I tried to add an Update Panel but I decided to come back to it when I was ready....Thanks for any help

       <asp:Panel ID="pnlAcknowledge" runat="server">
            <table id="tblGridview" runat="server" style="width:100%;">
            <tr>
                <td style="width:50%">
                    <asp:Label ID="lblDocType" runat="server" Text="Handbook Versions" Font-Bold="true" Font-Size="Medium"> </asp:Label>
                </td>               
            </tr>
            <tr style="width:100%">
                <td>
<%--                <asp:UpdatePanel runat="server">
                    <ContentTemplate>--%>
                    <asp:Panel ID="pnlGridview" runat="server">
                        <asp:GridView ID="gvDocuments" runat="server" AutoGenerateColumns="false" HorizontalAlign="Center" Width="95%" 
                            DataKeyNames="VersionID"  
                            onrowcancelingedit="gvDocuments_RowCancelingEdit"
                            onrowediting="gvDocuments_RowEditing"            
                            onrowdeleting="gvDocuments_RowDeleting"
                            onrowupdating="gvDocuments_RowUpdating">

                            <Columns>                       
                                                       
                            <asp:TemplateField HeaderStyle-HorizontalAlign="left" ItemStyle-HorizontalAlign="left" HeaderText="Latest" ItemStyle-Width="50px">
                                <ItemTemplate>
                                    <asp:HiddenField ID="hLatest" runat="server" Value='<%# Eval("Latest")%>' />                      
                                    <asp:CheckBox ID="chkLatest" runat="server" Checked='<%# Eval("Latest")%>'  OnCheckedChanged="chkLatest_CheckedChanged" AutoPostBack="true"/>
                                </ItemTemplate>
                            </asp:TemplateField>
                            
                            <asp:TemplateField HeaderText="File Name" ItemStyle-Width="350px">
                                <ItemTemplate>   
                                    <%#Eval("Name")%>   
                                </ItemTemplate>
                                <EditItemTemplate>
                                    <asp:TextBox ID="txtFileName" runat="server" Text='<%#Eval("Name") %>'></asp:TextBox>
                                </EditItemTemplate>
                            </asp:TemplateField>

                            <asp:TemplateField HeaderText="File Content">
                                <ItemTemplate>   
                                    <%#Eval("Content")%>   
                                </ItemTemplate>
                                <EditItemTemplate>
                                    <asp:TextBox ID="txtFileContent" runat="server" Text='<%#Eval("Content")%>'></asp:TextBox>
                                </EditItemTemplate>
                            </asp:TemplateField>

                            <asp:TemplateField HeaderStyle-HorizontalAlign="Center" ItemStyle-HorizontalAlign="center" HeaderText="View PDF Files" ItemStyle-Width="180px">
                                <ItemTemplate>
                                    <asp:LinkButton ID="lnkView" runat="server" Text="View" OnClick="View" CommandArgument='<%# Eval("VersionId")%>'></asp:LinkButton>
                                </ItemTemplate>
                            </asp:TemplateField>

                             <asp:CommandField ShowEditButton="true" ButtonType ="Image" EditImageUrl="~/Image/modify.ico" UpdateImageUrl="~/Image/accept.png"
                            CancelImageUrl="~/Image/cancel.ico" HeaderText="Edit" ItemStyle-Width="50px"/>

                            <asp:CommandField ShowDeleteButton="true" ButtonType="Image" DeleteImageUrl="~/Image/delete.ico" HeaderText="Delete" ItemStyle-Width="50px"/> 
                            </Columns>

                        </asp:GridView>  
                    </asp:Panel>
<%--                    </ContentTemplate>
                    </asp:UpdatePanel>--%>
                </td>

            </tr>
        </table>
        </asp:Panel>

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Thanks