Can I safely delete all files in my Windows 10 \temp\ folder?

Hi,

I'm running a Windows 10 Pro system. I'm trying to resolve a connection issue I have with Adobe servers. Can I safely delete ALL files located in my 'temp' folder i.e. C:\Users\<user>\AppData\Local\Temp? I want to make sure there is nothing there that may be interfering with

Advice appreciated.