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Office 2010 unable to save files after upgrading to Windows 10

On one of my users computers we are unable to save any word documents. This started after upgrade to Windows 10

Error is "unable to save due to permissions" and it points to a temp file or something in the content.mso directory

Any help would be appreciated
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Edward Pamias
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Windows 10 upgrades sometimes breaks things. It's better to remove and reinstall.
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I did a repair which did not work. I then reinstalled and still did not help. Thank you
Did you try a different user profile? Logon as another user?
You should find the cause by using procmon to monitor access denials. Are you familiar with procmon?
https://technet.microsoft.com/en-us/sysinternals/bb896644
Click File tab | Options | Save and select "Save to Computer by default." Also, if you select "Don't show the Backstage when opening or saving files," you can use the built-in keyboard shortcut Ctrl+O to quickly display the Open dialog box and you can use F12 to display the Save As dialog box.
I will be back at my office in an hour. I will try the recommended solutions and let you know

Thanks all
I do not see that setting in office 2010.  Must be a later version setting?
Do you see Save under options?
Just make sure you have rights to the folder you are saving to.
Strange. It only does that on network files but permissions are fine because other programs work. And the error message is from a temp location
"the error message is from a temp location" - details, please :-)
Message is

Word cannot complete the save due to a file permissions error c:\users\user\...\2AA9553E.tmp)

Even though the fine is on network location
Ok, please open explorer and try to create a text file under c:\users\user\... - does that work?
If yes, is that file you named still there, can you please verify the permissions on that file?
Permissions look good on text file
Even stranger. When I hit save it gives me the error above. Then I cancel out. Hit save again it give me an error that it can't save because being used by another process. Then I cancel out of that and hit save again and it works.

Then every time we save it has to go through same steps
Do you think rolling back to win 7 will solve?  I just upgraded yesterday to win 10
Wait, let's get back to "is that file you named still there, can you please verify the permissions on that file? (c:\users\user\...\2AA9553E.tmp)"
Yes. Fine is still there and permissions look good
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But this is happening on every document and just started after win 10 upgrade
Ok, then it is a very peculiar effect. We upgraded almost all our 8.1 machines to 10 and none of them showed this (not more often than before).
You can rollback to 7 for a test. Make sure to save all newly created files before you do that.
Thank you. I will post the results.
Ended up going back to windows 7, then reinstalling office and upgrading.
And now it's gone? Scary.
Well yes.  I went back to 7 then back to 10 and was still there. I then went back to 7 and completely uninstalled office. Then upgraded to 10 again and installed fresh and it is now working.  Strange but happy it worked

Thanks again!