Exchange Server 2013 Enterprise - Error MSExchange ADAccess Event ID 4113

I am having an issue with my Exchange Server saying:

Log Name:      Application
Source:        MSExchange ADAccess
Date:          8/1/2016 9:10:17 AM
Event ID:      4113
Task Category: General
Level:         Error
Keywords:      Classic
User:          N/A
Computer:      server
Description:
Process powershell.exe (EMS) (PID=25908). Component: Microsoft.Exchange.Data.Directory.ConfigurationSettingsADNotificationException: Error running AD operation. ---> Microsoft.Exchange.Data.Directory.ADTransientException: Could not find any available Domain Controller.
   at Microsoft.Exchange.Data.Directory.ConnectionPoolManager.GetConnection(ConnectionType connectionType, String partitionFqdn, ADObjectId domain, String serverName, Int32 port, NetworkCredential credential)
   at Microsoft.Exchange.Data.Directory.ADDataSession.GetConnection(String preferredServer, Boolean isWriteOperation, String optionalBaseDN, ADObjectId& rootId, ADScope scope)
   at Microsoft.Exchange.Data.Directory.ADDataSession.GetReadConnection(String preferredServer, String optionalBaseDN, ADObjectId& rootId, ADRawEntry scopeDeteriminingObject)
   at Microsoft.Exchange.Data.Directory.ADDataSession.InternalFind[TResult](ADObjectId rootId, String optionalBaseDN, ADObjectId readId, QueryScope scope, QueryFilter filter, SortBy sortBy, Int32 maxResults, IEnumerable`1 properties, Boolean includeDeletedObjects)
   at Microsoft.Exchange.Data.Directory.ADDataSession.Find[TResult](ADObjectId rootId, QueryScope scope, QueryFilter filter, SortBy sortBy, Int32 maxResults, IEnumerable`1 properties, Boolean includeDeletedObjects)
   at Microsoft.Exchange.Data.Directory.ADDataSession.Find[TResult](ADObjectId rootId, QueryScope scope, QueryFilter filter, SortBy sortBy, Int32 maxResults)
   at Microsoft.Exchange.Data.Directory.SystemConfiguration.ADSystemConfigurationSession.GetRootOrgContainer(String partitionFqdn, String domainController, NetworkCredential credential)
   at Microsoft.Exchange.Data.Directory.SystemConfiguration.ConfigurationSettings.ADConfigDriver.<>c__DisplayClass2.<LoadSettings>b__0()
   at Microsoft.Exchange.Data.Directory.ADNotificationAdapter.RunADOperation(ADOperation adOperation, Int32 retryCount)
   at Microsoft.Exchange.Data.Directory.ADNotificationAdapter.TryRunADOperation(ADOperation adOperation, Int32 retryCount)
   --- End of inner exception stack trace ---. Unable to load application settings. Exception: '%4'
Event Xml:
<Event xmlns="http://schemas.microsoft.com/win/2004/08/events/event">
  <System>
    <Provider Name="MSExchange ADAccess" />
    <EventID Qualifiers="49152">4113</EventID>
    <Level>2</Level>
    <Task>1</Task>
    <Keywords>0x80000000000000</Keywords>
    <TimeCreated SystemTime="2016-08-01T14:10:17.000000000Z" />
    <EventRecordID>637930</EventRecordID>
    <Channel>Application</Channel>
    <Computer>server</Computer>
    <Security />
  </System>
  <EventData>
    <Data>powershell.exe (EMS)</Data>
    <Data>25908</Data>
    <Data>Microsoft.Exchange.Data.Directory.ConfigurationSettingsADNotificationException: Error running AD operation. ---&gt; Microsoft.Exchange.Data.Directory.ADTransientException: Could not find any available Domain Controller.
   at Microsoft.Exchange.Data.Directory.ConnectionPoolManager.GetConnection(ConnectionType connectionType, String partitionFqdn, ADObjectId domain, String serverName, Int32 port, NetworkCredential credential)
   at Microsoft.Exchange.Data.Directory.ADDataSession.GetConnection(String preferredServer, Boolean isWriteOperation, String optionalBaseDN, ADObjectId&amp; rootId, ADScope scope)
   at Microsoft.Exchange.Data.Directory.ADDataSession.GetReadConnection(String preferredServer, String optionalBaseDN, ADObjectId&amp; rootId, ADRawEntry scopeDeteriminingObject)
   at Microsoft.Exchange.Data.Directory.ADDataSession.InternalFind[TResult](ADObjectId rootId, String optionalBaseDN, ADObjectId readId, QueryScope scope, QueryFilter filter, SortBy sortBy, Int32 maxResults, IEnumerable`1 properties, Boolean includeDeletedObjects)
   at Microsoft.Exchange.Data.Directory.ADDataSession.Find[TResult](ADObjectId rootId, QueryScope scope, QueryFilter filter, SortBy sortBy, Int32 maxResults, IEnumerable`1 properties, Boolean includeDeletedObjects)
   at Microsoft.Exchange.Data.Directory.ADDataSession.Find[TResult](ADObjectId rootId, QueryScope scope, QueryFilter filter, SortBy sortBy, Int32 maxResults)
   at Microsoft.Exchange.Data.Directory.SystemConfiguration.ADSystemConfigurationSession.GetRootOrgContainer(String partitionFqdn, String domainController, NetworkCredential credential)
   at Microsoft.Exchange.Data.Directory.SystemConfiguration.ConfigurationSettings.ADConfigDriver.&lt;&gt;c__DisplayClass2.&lt;LoadSettings&gt;b__0()
   at Microsoft.Exchange.Data.Directory.ADNotificationAdapter.RunADOperation(ADOperation adOperation, Int32 retryCount)
   at Microsoft.Exchange.Data.Directory.ADNotificationAdapter.TryRunADOperation(ADOperation adOperation, Int32 retryCount)
   --- End of inner exception stack trace ---</Data>
  </EventData>
</Event>

I've been scouring the Internet and found things relating back to 2007 and 2010 but not 2013 in particular.  I've tried some of the 2010 items to no avail.  One of the issues I'm trying to get to the bottom to is the inability to access the properties of resource mailbox pages.  Where it was an old one or a new one, I get a 500 error when I try to edit it.

Anyone see this before or have any thoughts on how best to fix this?

Regards,

Jason