Visual basic 2012 filtering datagrid view data

I am a beginner in Visual basic 2012 and making a data management programme with visual basic 2012 as front end and MySql as back end. I want to filter data grid view table with combo box , checked listbox and List box (multiple selected) . When I select one item it works fine and when I select multiple items in the List box I do not have code can u help me please. I am able to get all the items of a column in the list box by following code

Query = "Select * from `rrrr.data`.`trial` " 
COMMAND = New MySqlCommand(Query, MySqlConn)
READER = COMMAND.ExecuteReader
While READER.Read
Dim sCountry = READER.GetString("COUNTRY")
ListBox1.Items.Add(sCountry)
End While

But for filtering data when I use below query it does not work ( for multiple selected or more than one item ) It does not work Query which I use is-
Query = "Select * from `rrrr.data`.`trial` Where `COUNTRY`in (''" & ListBox1.SelectedItem& "'' )"

Kindly help me out  in filtering data using  combo box , checked list box and List box ,. my requirement is to filter data as per the selected column and multiple  selected items of the a selected column.