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Soryy if this sounds too obvious but have seen it too many timed - is IP comms working at all, e.g. default gateway points elsewhere or you have the wrong subnet mask or second nic with an ip from the other site.<br />
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Check routing table with route print from cmd and tracer or pathping with ip of other site to see where it stops.<br />
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Where does your site vpn come in - from a server or same router as internet. If your default gateway points out to a local Internet connection you might need a static route on there too your other site via the vpn device.<br />
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Steve
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The issue was the Kaspersky firewall. Thanks guys for your help.
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I setup and configured a new dc at one of my companies locations. Between Office1 and Office2 (new dc), &nbsp;we have a site-to-site vpn tunnel. I can ping devices at Office1 from Office2 just fine but I can't ping the virtual host which is where the new dc lives. From the new dc I can ping other dc's on my network just fine but I can't ping the new dc from the other dc's. There are other servers at Office2 that I can ping and remote into from Office1 but for some reason I can't ping or remote into the virtual host. To get to the virtual host I have to remote into a different server in Office2 then remote into the virtual host.
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I setup and configured a new dc at one of my companies locations. Between Office1 and Office2 (new dc),  we have a site-to-site vpn tunnel. I can ping devices at Office1 from Office2 just fine but I can't ping the virtual host which is where the new dc lives. From the new dc I can ping other dc's on my network just fine but I can't ping the new dc from the other dc's. There are other servers at Office2 that I can ping and remote into from Office1 but for some reason I can't ping or remote into the virtual host. To get to the virtual host I have to remote into a different server in Office2 then remote into the virtual host.

Cannot connect to Domain Controller

The Domain Name System (DNS) is a hierarchical, globally distributed system responsible for associating the name of a computer, service or other resource into an IP address for connecting to the Internet or a private network. Most prominently, it translates domain names to the numerical IP addresses needed for the purpose of computer services and devices worldwide.

Active Directory (AD) is a Microsoft brand for identity-related capabilities. In the on-premises world, Windows Server AD provides a set of identity capabilities and services, and is hugely popular (88% of Fortune 1000 and 95% of enterprises use AD). This topic includes all things Active Directory including DNS, Group Policy, DFS, troubleshooting, ADFS, and all other topics under the Microsoft AD and identity umbrella.

Active Directory

The Windows operating systems have distinct methodologies for designing and implementing networks, and have specific systems to accomplish various networking processes, such as Exchange for email, Sharepoint for shared files and programs, and IIS for delivery of web pages. Microsoft also produces server technologies for networked database use, security and virtualization.