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1.Is the user logged in to Outlook Web Access anywhere?<br />
2.On the workstation..Control Panel&gt;User Accounts&gt;Manage Your Credentials &nbsp; remove any old entries for outlook, etc.
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When I reset a users password in the active directory i can logon to the users email no problem when. <br />
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when I close outlook and reopen it outlook will ask for a domain login but the account is locked.
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When I reset a users password in the active directory i can logon to the users email no problem when. 

when I close outlook and reopen it outlook will ask for a domain login but the account is locked.

Weird Outlook Error

Exchange is the server side of a collaborative application product that is part of the Microsoft Server infrastructure. Exchange's major features include email, calendaring, contacts and tasks, support for mobile and web-based access to information, and support for data storage.

Exchange

Microsoft Outlook is a personal information manager from Microsoft, available as a part of the Microsoft Office suite. Although often used mainly as an email application, it also includes a calendar, task manager, contact manager, note-taker, journal, and web browser.