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@edpowell19 - Did you try my suggestion? &nbsp;It will work.
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I apologize for the abandonment. As it turns out, the problem was caused by a rogue DHCP server. Once found and turned off everything is functioning properly. <br />
Thanks to all of those who offered suggestions.
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After the Windows 10 Anniversary update a client attempting to map drives on a 2008 R2 server sees the mapped drives X'd out. If we click on one of the failed mappings we are prompted to login to the domain again at which time we're granted access.<br />
How do we fix this?
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After the Windows 10 Anniversary update a client attempting to map drives on a 2008 R2 server sees the mapped drives X'd out. If we click on one of the failed mappings we are prompted to login to the domain again at which time we're granted access.
How do we fix this?

Windows 10 Anniversary Update Clients cannot contact domain controller at initial login

Operating systems perform basic tasks, such as recognizing input from the keyboard, sending output to the display screen, keeping track of files and directories on the disk, and controlling peripheral devices such as disk drives and printers. For large systems, the operating system makes sure that different programs and users running at the same time do not interfere with each other. The operating system is also responsible for security, ensuring that unauthorized users do not access the system. Operating systems provide a software platform on top of which other programs, called application programs, can run.

Operating Systems

The Windows operating systems have distinct methodologies for designing and implementing networks, and have specific systems to accomplish various networking processes, such as Exchange for email, Sharepoint for shared files and programs, and IIS for delivery of web pages. Microsoft also produces server technologies for networked database use, security and virtualization.